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| Appointment(s) and Titles: |
Associate Professor, Medical Microbiology and Immunology, Creighton University
Associate Professor, Medicine, Creighton University
Associate Professor, Medicine, University of Nebraska Medical Center
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| Education: |
B.S., Combined Science, Youngstown State University, 1983
M.D., Northeastern Ohio Universities' College of Medicine, 1983
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| Research Interests: |
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Pathogenesis of Neisseria gonorrhoeae infections. I study this infection
in the human Fallopian tube organ culture model. Interactions of the bacteria with Fallopian tube epithelial
cells are quantified with a unique system that utilizes digital confocal microscopy and computerized image
analysis to measure bacterial attachment to and invasion of host cells.
Recently I constructed an E. coli model of the gonococcus by expressing several putative gonococcal
virulence factors simultaneously in E. coli. This model can be used in the Fallopian tube organ
culture system to determine the roles of these factors alone and together in the pathogenesis of gonococcal
salpingitis.
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| Selected
Publications: |
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| Honors & Awards |
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National Board of Medical Examiners board certified, Internal Medicine, 1986
National Board of Medical Examiners board certified, Infectious
Disease, 1989
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