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| Appointment(s) and Titles: |
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Professor, Medical
Microbiology and Immunology
Associate Director, Center for Research in Anti-Infectives and
Biotechnology
Director, Graduate Program, Medical Microbiology and
Immunology
Director, Regional VI, American Society for Microbiology
Branch Organizing Committee, American Society for Microbiology
Past President, Missouri Valley Branch, American Society for
Microbiology
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| Education: |
B.S., Kansas State University, Microbiology,
1986
M.S., Creighton University, Medical Microbiology, 1989
Ph.D., Creighton University, Medical Microbiology, 1992
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| Research Interests: |
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The use of animal models of infection and an in
vitro pharmacokinetic model to evaluate pharmacodynamic
interactions between antimicrobial agents and bacteria, including: 1) Evaluation of new dosing strategies for
the treatment of infections; 2) Role of Û†lactamase
inhibitor pharmacokinetics on the dynamic interactions of
Û†lactamase†inhibitor/Û†lactam
combinations; 3) Pharmacodynamics of drug combinations against
bacteria, 4) Development of resistance during therapy.
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| Selected
Publications: |
Lister PD. Multiply-Resistant Pneumococcus:
Therapeutic Problems in the Management of Serious Infections. Eur J
Clin Mic Infect Dis 1994;14 (Supplement 1):S18-S25.
Lister PD, Sanders CC. Pharmacodynamics of trovafloxacin,
ofloxacin, and ciprofloxacin against Streptococcus pneumoniae in an
in vitro pharmacokinetic model. Antimicrobial Agents and
Chemotherapy. Antimicrobial Agents and Chemotherapy
1999;43:1118-1123.
Lister PD, Gardner VM, Sanders CC. Clavulanate induces expression
of the P. aeruginosa AmpC cephalosporinase at
physiologically-relevant concentrations and antagonizes the
antibacterial activity of ticarcillin. Antimicrobial Agents and
Chemotherapy. 1999;43:882-889.
Lister PD, Sanders, WE, Jr., Sanders CC. Cefepime-aztreonam: a
unique double *-lactam combination for Pseudomonas aeruginosa.
Antimicrobial Agents and Chemotherapy 1998; 42: 1610-1619.
Lister PD, Pong A, Chartrand SC, Sanders CC. Rationale behind
high-dose amoxicillin therapy for otitis media due to
penicillin-nonsusceptible pneumococci: support from in vitro
pharmacodynamic studies. Antimicrobial Agents and Chemotherapy
1997;41: 1926-1932.
Lister PD, Prevan AM, Sanders, CC. Importance of ß-Lactamase
Inhibitor Pharmacokinetics in the Pharmacodynamics of
Inhibitor-Drug Combinations: Studies with Pipercillin-Tazobactam
and Pipercillin-Sulbactam. Antimicrobial Agents and Chemotherapy
1997; 41:721-727.
Alexov M, Lister PD, Sanders CC. Efficacy of Ampicillin-Sulbactam
is Not Dependent Upon Maintenance of a Critical Ratio Between
Components: Sulbactam Pharmacokinetics in Pharmacodynamic
Interactions. Antimicrob. Agents Chemother. 1996;40:2468-2477.
Lister PD, Gentry MJ, Preheim LC. Granulocyte Colony-Stimulating
Factor Protects Control Rats but Not Ethanol-Fed Rats from Fatal
Pneumococcal Pneumonia. J Infect Dis 1993;168:922-6.
Lister PD, Gentry MJ, Preheim LC. Ethanol Impairs Neutrophil
Chemotaxis In Vitro but Not Adherence or Recruitment to Lungs of
Rats with Experimental Pneumococcal Pneumonia. J Infect Dis
1993;167:1131-7.
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| Current
Teaching: |
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MIC541 – Medical Microbiology &
Immunology (Course Director)
o Introduction to Medical Microbiology and Immunology.
Characteristics of bacteria, gram-negative coccobacilli,
gram-negative enterics and miscellaneous bacteria. Antibacterial
drugs.
MIC 753 - Antimicrobial Agents and Chemotherapy (Course
Director)
o Pharmacodynamic of antimicrobials, penicillin-binding proteins,
bacteriostatic drugs, antifungal agents, cell-wall active agents,
Fluoroquinolones, Glycopeptide resistance.
MIC727 – Methods in Medical Microbiology and Immunology
o Thesis preparation
ORB135 - Oral Microbiology
- Haemophilus, Bordetella,Vibrio, Campylobacter, Group A
Streptococcal Sequelae, Bacterial Endocarditis
MIC735 - Diagnostic Microbiology
- Antimicrobial susceptibility testing
procedures
- Antimicrobial Agents and Chemotherapy
Mini-Course
- Member of Faculty for summer courses for
representatives from microbiological and pharmaceutical
- industry. Coordinate laboratories and lecture on
anti-fungal agents.
- Introduction to Clinical Laboratory and
Antimicrobial Susceptibility Testing
- Pediatric infectious disease fellows, residents,
interns, and medical students
| Mentoring: |
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Director of Graduate Program
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| Professional
Activities: |
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Foundation Lecturer: American Society for
Microbiology
Council Member, American Society for Microbiology, 1999-2001
President, Missouri Valley Branch of the American Society for
Microbiology 1997-Present
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| Honors &
Awards: |
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Pioneer Award - Recognition of leadership role and
contribution to the science of hollow fiber bioreactor
technology.
Presented at 1997 BioSym International Symposium on Hollow-Fiber
Technology
Premier Research Award - Omaha Mid-West Clinical Society 64th
Annual Postgraduate Assembly
Who's Who in Science and Engineering
Bristol-Myers Squibb Scholar
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